Improving Symptoms of Peripheral Artery Disease With Hirudotherapy
Case report published in Cureus (2021)
Abstract
Peripheral artery disease (PAD) is a significant cause of morbidity and mortality in the world. Critical limb ischemia is a complication of PAD that leads to severe pain at rest, numbness, and absent or diminished pulses in the legs or feet. Revascularization with surgery or endovascular intervention is required to re-establish blood flow to the affected areas. Failure to respond to medical and/or surgical treatment can lead to amputations. The decision to amputate one's limb can be very challenging. Here, we report a patient with critical limb ischemia who refused a below-the-knee amputation and self-treated with medicinal leech therapy, or hirudotherapy. His symptoms including his pain, burning, and numbness improved significantly following six months of therapy.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Summary
A patient with critical limb ischemia who refused below-the-knee amputation self-treated with medicinal leech therapy for six months, after which his pain, burning and numbness improved significantly, as illustrated by this case report.
Why This Matters for Hirudotherapy
This case report describes a patient with critical limb ischemia from peripheral artery disease who refused a recommended below-the-knee amputation and self-treated with medicinal leech therapy over six months. The authors report that the patient's pain, burning, and numbness improved significantly following this treatment. This report is directly relevant to hirudotherapy as it documents symptomatic outcomes of leech therapy in a limb ischemia context where amputation had been recommended and declined. However, as a single case report of patient self-administered therapy, it provides limited anecdotal evidence and cannot establish efficacy, safety, or generalizability of hirudotherapy for critical limb ischemia or peripheral artery disease.
Citation
Added to ASH library: March 18, 2026 · Site last updated: November 1, 2026