Leech Therapy in Flap Salvage — Timing and Practical Recommendations
Systematic review establishing timing of leech application as the dominant prognostic factor
Summary
Systematic review of leech therapy for flap salvage with practical clinical recommendations. Identified timing of leech application as the single most important prognostic factor: early application (within 6 hours of congestion onset) significantly improved salvage rates compared to delayed treatment.
Why This Matters for Hirudotherapy
Translates research evidence into actionable clinical guidance. The finding that timing is the dominant variable has directly shaped institutional protocols, emphasizing the need for immediate leech availability in microsurgery units and round-the-clock monitoring for venous congestion signs.
Citation
Leech Therapy in Flap Salvage: Systematic Review and Practical Recommendations
Herlin C et al. · Journal of Plastic, Reconstructive & Aesthetic Surgery, 2017
Added to ASH library: March 18, 2026 · Site last updated: March 18, 2026