American Society of Hirudotherapy

Lower extremity microsurgical reconstruction.

Review published in Plastic and reconstructive surgery (2001)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Narrative reviewClinical TrialsHeller et al. · Plastic and reconstructive surgery, 2001

Abstract

After studying this article, the participant should be able to: 1. Understand the indications for the use of free-tissue transfer in lower extremity reconstruction. 2. Understand modalities to enhance the healing and care of soft tissue and bone before free-tissue transfer. 3. Understand the lower extremity reconstructive ladder and the place of free-tissue transfer on the ladder. 4. Understand the specific principles of leg, foot, and ankle reconstruction. 5. Understand the factors that influence the decision to perform an immediate versus a delayed reconstruction. Free-tissue transfer using microsurgical techniques is now routine for the salvage of traumatized lower extremities. Indications for microvascular tissue transplantation for lower extremity reconstruction include high-energy injuries, most middle and distal-third tibial wounds, radiation wounds, osteomyelitis, nonunions, and tumor reconstruction. The authors discuss the techniques and indications for lower extremity reconstruction.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal ArticleReview
Indexed MeSH termsBone NeoplasmsCosts and Cost AnalysisForecastingHumansInformed ConsentLegLeg InjuriesMicrosurgeryOrthopedic ProceduresPlastic Surgery ProceduresSoft Tissue NeoplasmsSurgical Flaps

Summary

After studying this article, the participant should be able to: 1. Understand the indications for the use of free-tissue transfer in lower extremity reconstruction.

Why This Matters for Hirudotherapy

This review discusses indications, techniques, and principles for lower extremity microsurgical reconstruction using free-tissue transfer, covering scenarios such as high-energy injuries, radiation wounds, osteomyelitis, nonunions, and tumor reconstruction. The authors outline the reconstructive ladder and factors influencing immediate versus delayed reconstruction. For ASH's domain, there is no direct connection: the abstract does not mention leeches, hirudotherapy, or the leech secretome. While medicinal leeches are sometimes used adjunctively in microsurgical flap salvage for venous congestion, this application is not referenced in the abstract. Its relevance to ASH is negligible to indirect at best — limited only to the general clinical context of microsurgery where leech therapy might occasionally be employed as a salvage adjunct.

Citation

Lower extremity microsurgical reconstruction.

Heller et al. · Plastic and reconstructive surgery, 2001

Added to ASH library: May 28, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.