American Society of Hirudotherapy

Management of complications and compromised free flaps following major head and neck surgery

Retrospective cohort published in Eur Arch Otorhinolaryngol (2015)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportClinical LiteratureSafety & Infection ControlKucur C et al. · European archives of oto-rhino-laryngology, 2016

Abstract

Microvascular free flaps are preferred for most major head and neck reconstruction surgeries because of better functional outcomes, improved esthetics, and generally higher success rates. Numerous studies have investigated measures to prevent flap loss, but few have evaluated the optimal treatment for free flap complications. This study aimed to determine the complication rate after free flap reconstructions and discusses our management strategies. Medical records of 260 consecutive patients who underwent free flap reconstructions for head and neck defects between July 2006 and June 2010 were retrospectively reviewed for patient and surgical characteristics and postoperative complications. The results revealed that microvascular free flaps were extremely reliable, with a 3.5 % incidence of flap failure. There were 78 surgical site complications. The most common complication was neck wound infection, followed by dehiscence, vascular congestion, abscess, flap necrosis, hematoma, osteoradionecrosis, and brisk bleeding. Twenty patients with poor wound healing received hyperbaric oxygen therapy, which was ineffective in three patients who eventually experienced complete flap loss. Eleven patients with vascular congestion underwent medicinal leech therapy, which was effective. Among the 78 patients with complications, 44 required repeat surgery, which was performed for postoperative brisk bleeding in three. Eventually, ten patients experienced partial flap loss and nine experienced complete flap loss, with the latter requiring subsequent pectoralis major flap reconstruction. Microvascular free flap reconstruction represents an essential and reliable technique for head and neck defects and allows surgeons to perform radical resection with satisfactory functional results and acceptable complication rates.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsFemaleFree Tissue FlapsHead and Neck NeoplasmsHematomaHumansHyperbaric OxygenationMaleMiddle AgedNeck DissectionOhioOsteoradionecrosisPostoperative ComplicationsPlastic Surgery ProceduresReoperationRetrospective Studies

Summary

Reviewing 260 consecutive head and neck free flap reconstructions, this study reports a 3.5% flap failure rate and describes management of complications, including medicinal leech therapy that was effective in 11 patients with vascular congestion.

Why This Matters for Hirudotherapy

This study retrospectively reviewed medical records of 260 consecutive patients who underwent free flap reconstruction for head and neck defects between July 2006 and June 2010, reporting a 3.5% incidence of flap failure and 78 surgical site complications. The abstract states that, among management strategies, eleven patients with vascular congestion were treated with medicinal leech therapy, which was effective. This provides a clinical report of leech therapy used for vascular congestion in compromised head and neck free flaps. No details are given regarding leech species, protocol, duration, complications, or comparative effectiveness, and leech therapy is a secondary element within a broader surgical-complication management study.

Citation

Reference (Vancouver style)

Kucur C, Durmus K, Uysal IO, Old M, Agrawal A, Arshad H, et al. Management of complications and compromised free flaps following major head and neck surgery. Eur Arch Otorhinolaryngol. 2016;273(1):209-213. doi:10.1007/s00405-014-3489-1. PMID: 25575841

Bibliographic details (authors, volume, pages, DOI) are taken from the PubMed record.

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.