American Society of Hirudotherapy

Postoperative Digit and Hand Replantation Protocols: A Review of the Literature

Review published in J Am Acad Orthop Surg (2021)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportClinical TrialsChen C et al. · The Journal of the American Academy of Orthopaedic Surgeons, 2021

Abstract

Successful replantation and revascularization of the hand and digit require a skilled team with urgent access to an operating room with microsurgical capabilities. Although careful indications and surgical techniques contribute to success, postoperative management also plays a vital role in the survival of a replanted digit. Previous research has assessed surgical efficiency and techniques to conduct these procedures, but few studies evaluate postoperative protocols to care for patients undergoing these procedures. Because of the lack of high-level evidence specific to replantation, many common postoperative practices related to monitoring, anticoagulation, and diet have been inferred from elective microsurgical procedures, despite notable differences in operating conditions. The highest level of evidence pertaining to digital replantation was found with the use of peripheral nerve blockade, leeching/bleeding, and nicotine use. This review provides an in-depth evaluation of the literature and insight into the rationale and level of evidence that support each postoperative intervention. It highlights institutional variability and a paucity of high-level evidence pertaining to this topic while identifying the areas of future research.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsAmputation, TraumaticFinger InjuriesFingersHandHumansReplantationReview Literature as TopicVascular Surgical Procedures

Summary

Literature review of postoperative replantation protocols highlighting leeching/bleeding as one of highest-level-evidence interventions alongside peripheral nerve blockade and nicotine avoidance.

Why This Matters for Hirudotherapy

This literature review evaluated postoperative management protocols for hand and digit replantation and revascularization, noting that many common practices related to monitoring, anticoagulation, and other measures are inferred from elective microsurgical procedures due to limited replantation-specific evidence. The abstract identifies the highest level of evidence pertaining to digital replantation as found with peripheral nerve blockade, leeching/bleeding, and nicotine use. For ASH's domain, this review is relevant because it explicitly identifies leeching/bleeding as one of the few postoperative replantation interventions with higher-level evidentiary support, a recognized hirudotherapy application. However, the abstract provides no specifics on leech protocols, outcomes, or the strength/grade of that evidence; the review highlights institutional variability and a paucity of high-level evidence overall, so its leech-therapy relevance is confirmatory but not detailed.

Citation

Postoperative Digit and Hand Replantation Protocols: A Review of the Literature.

Chen C et al. · The Journal of the American Academy of Orthopaedic Surgeons, 2021

Added to ASH library: May 27, 2026 · Site last updated: June 18, 2026

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