American Society of Hirudotherapy

Factors associated with early and late digital revascularization and replantation failure: a retrospective cohort study

Retrospective cohort published in J Hand Surg Eur Vol (2021)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportClinical TrialsFlorczynski M et al. · The Journal of hand surgery, European volume, 2021

Abstract

Factors associated with failure of digital revascularization and replantation procedures have been well characterized, but studies have not investigated failures occurring beyond the early postoperative period. A single-centre retrospective chart review included 284 patients (434 digits) who underwent digital revascularization or replantation. Patient-, injury- and surgery-related characteristics were compared among successful procedures, digits that failed while in hospital (early failure), and initially viable digits that failed after hospital discharge (late failure). Overall, 202 patients had successful procedures (71%). There were 51 early failures (18%) and 31 late failures (11%). Crush injuries and vein grafting were associated with early failure only. Complete amputations and leeching were strongly associated with both early and late failure. This study revealed that a substantial proportion of initially viable digits fail after discharge from hospital. Patients with signs of venous congestion may benefit from longer observation periods in hospital to avoid late failure.Level of evidence: IV.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsAmputation, TraumaticFinger InjuriesFingersHumansReplantationRetrospective Studies

Summary

In 284 patients and 434 digits, leeching was strongly associated with both early (in-hospital) and late (post-discharge) failure of digital revascularization or replantation. 11% of initially viable digits failed after discharge.

Why This Matters for Hirudotherapy

This single-centre retrospective chart review included 284 patients (434 digits) who underwent digital revascularization or replantation, comparing patient-, injury-, and surgery-related characteristics among successful procedures, early failures (in hospital), and late failures (after discharge). The study found that complete amputations and leeching were strongly associated with both early and late failure. For ASH's domain, this study documents leeching as a factor present in a subset of digital revascularization and replantation cases at this centre. The honest caveat is that the abstract reports only an association between leeching and failure; it does not address the nature of leeching use or its causal role in outcomes, and the study was designed to identify factors associated with failure rather than to evaluate leech therapy itself.

Citation

Factors associated with early and late digital revascularization and replantation failure: a retrospective cohort study.

Florczynski M et al. · The Journal of hand surgery, European volume, 2021

Added to ASH library: May 26, 2026 · Site last updated: June 18, 2026

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