American Society of Hirudotherapy

Complexities in pediatric tuberculosis: a case of advanced disease complicated by deep vein thrombosis and enterocutaneous fistula from Ethiopia

Research article published in BMC infectious diseases (2026)

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportClinical TrialsSafety & Infection ControlBogale A et al. · BMC infectious diseases, 2026

Abstract

Tuberculosis (TB) remains a leading global infectious disease, causing nearly 4,000 deaths daily, particularly affecting children under five. This case illustrates the complexities of diagnosing and treating advanced tuberculosis complications in a 6-year-old child who presented with deep vein thrombosis (DVT), an enterocutaneous fistula, and malnourishment. Causality was called into question by the connection between these conditions. Antibiotics, anticoagulants, antituberculosis drugs, fresh frozen plasma, stoma bag wound care, and nutritional support were all part of the patient’s treatment. She was discharged from the hospital with improvement after 15 days. The complex relationships among venous thromboembolism, malnourishment, and chronic infection are highlighted in this instance, underscoring the necessity of timely and thorough management of advanced TB to address the nutritional and infectious components of the patient’s condition. Not applicable.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article

Summary

Tuberculosis (TB) remains a leading global infectious disease, causing nearly 4,000 deaths daily, particularly affecting children under five. This case illustrates the complexities of diagnosing and treating advanced tuberculosis complications in a 6-year-old child who presented with deep vein thrombosis (DVT), an enterocutaneous fistula, and malnourishment.

Why This Matters for Hirudotherapy

Informs anticoagulation and antithrombotic management relevant to hirudotherapy's clinical context.

Citation

Complexities in pediatric tuberculosis: a case of advanced disease complicated by deep vein thrombosis and enterocutaneous fistula from Ethiopia.

Bogale A et al. · BMC infectious diseases, 2026

Added to ASH library: May 28, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.