American Society of Hirudotherapy

Beneficial effects of hirudotherapy in a chronic case of complex regional pain syndrome

Research article published in Journal of integrative medicine (2019)

Last Updated: March 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Clinical TrialsKulbida R, Mathes A, Loeser J · Journal of integrative medicine, 2019

Abstract

We report about hirudotherapy in a patient with chronic complex regional pain syndrome (CRPS) in the right hand. CRPS is a multifactorial disease associated with disabling pain as well as sensory and motor deficits. The optimal therapeutic management is based on personalized multimodal treatment approaches; however, hirudotherapy has not been described in the available literature. To date, we have completed five medicinal leech treatments. Altogether, hirudotherapy led to rapid and substantial relief of symptoms, especially with respect to pain intensity ratings and skin temperature asymmetries. In addition, the patient's active and passive agility of the affected limb improved obviously.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeCase ReportsJournal Article
Indexed MeSH termsComplex Regional Pain SyndromesHandHumansLeechingMaleMiddle AgedPain MeasurementSkin Temperature

Summary

We report about hirudotherapy in a patient with chronic complex regional pain syndrome (CRPS) in the right hand. CRPS is a multifactorial disease associated with disabling pain as well as sensory and motor deficits.

Why This Matters for Hirudotherapy

Contributes clinical evidence for the therapeutic application of leech therapy.

Citation

Beneficial effects of hirudotherapy in a chronic case of complex regional pain syndrome.

Kulbida R, Mathes A, Loeser J · Journal of integrative medicine, 2019

Added to ASH library: March 18, 2026 · Site last updated: March 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.

Beneficial effects of hirudotherapy in a chronic case of complex regional pain syndrome | ASH