Smart Library
Faceted search across all 5 registries. Filter by registry type, evidence level, or safety domain.
New to hirudotherapy? Start here
This library indexes the full evidence base. For orientation, begin with the core guides:
Filters
Evidence level
Showing 6 of 755 entries. Refine via URL query params.
Conditions
6Chronic Rhinosinusitis
Tier BInvestigational use for chronic rhinosinusitis; no clinical study of leech therapy for this condition was identified, and the rationale is mechanistic.
Glaucoma (Adjunctive)
Tier CInvestigational adjunctive use in primary open-angle glaucoma; weak case-series evidence. Not a substitute for IOP-lowering eye drops or surgery.
Dry Eye Syndrome
Tier CInvestigational use for dry eye disease; no clinical study of leech therapy was identified, and the proposed meibomian-gland mechanism is hypothetical.
Rosacea (Erythematotelangiectatic)
Tier CInvestigational use for erythematotelangiectatic rosacea; no clinical study of leech therapy was identified.
Rosacea (Papulopustular Subtype)
Tier CInvestigational adjunct for papulopustular rosacea with persistent inflammatory lesions; evidence is one small uncontrolled Ayurvedic study.
Thyroid Eye Disease (Investigational Periocular Adjunct)
Tier CHighly investigational periocular adjunct for stable thyroid eye disease; ocular risk is critical; teprotumumab and orbital decompression remain primary.