American Society of Hirudotherapy

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What is hirudotherapy?Conditions atlasClinical evidencePatient guide

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Showing 3 of 755 entries. Refine via URL query params.

Conditions

3

Venous Leg Ulcer

Tier B

Off-label adjunct to compression therapy; the evidence is one 20-patient uncontrolled series in complicated varicose veins plus case reports.

Studied off-labelCohort / case series

Congestive Heart Failure (Compensated, Investigational Adjunct)

Tier C

Investigational adjunct in compensated NYHA II heart failure; only small open-label or uncontrolled studies were identified, mostly in Russian-language sources; guideline-directed medical therapy remains primary.

InvestigationalCohort / case series

Adenomyosis (Investigational Palliative Adjunct)

Tier C

Investigational palliative adjunct for adenomyosis-related dysmenorrhea and pelvic pain; hormonal therapy (LNG-IUD, dienogest, GnRH antagonists) and (definitively) hysterectomy remain evidence-based.

InvestigationalCohort / case series

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.

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