American Society of Hirudotherapy

Partial salvage of avulsed tissue after dog bite

Øregaard JS, Lang CL, Venzo A (2015) · Annals of the Royal College of Surgeons of England · n=1

RCT evidence detailTrial reference
Sample size of this trial compared with other Microsurgical Replantation (Digit / Ear / Scalp) trialsArbel EJ 202446Battin AO 202312Hong Ha N 20254van Alphen NA 20142Øregaard JS 20151Akhoondinasab MR 20231Banihani OI 20141Mousa A 20221Mendenhall SD 20161Momeni A 20141
This trial (highlighted) by sample size alongside other indexed Microsurgical Replantation (Digit / Ear / Scalp) trials. Larger trials generally carry more statistical weight.

Study Profile

Design
single-patient case report (18-year-old woman, central facial dog bite injury, Rigshospitalet Copenhagen)
Sample size (n)
1
Intervention
Microsurgical arterial anastomosis for nasal tip replantation with leech therapy when venous anastomosis impossible; skin necrosis subsequently managed with revision and full-thickness skin graft
Comparator
No control - case report
Primary endpoint
Nasal tissue salvage and aesthetic outcome after dog bite avulsion
Primary result
Partial nasal salvage achieved through arterial-only anastomosis with leech therapy; subsequent skin necrosis required revision with full-thickness skin graft; satisfactory cosmetic and functional result at 8-month follow-up
Follow-up duration
8 months postoperative

Key Findings

  • Facial dog bite avulsion salvage with arterial-only anastomosis + leech
  • Subsequent skin necrosis required revision
  • Healthy tissue immediately below necrotic skin enabled FTSG closure
  • Satisfactory 8-month aesthetic outcome
  • Demonstrates leech utility in facial reconstruction context

Limitations

  • Single case - limited generalizability
  • Partial necrosis suggests leech alone insufficient
  • 8-month follow-up may not capture long-term outcomes
  • Subjective cosmetic assessment
  • Cannot quantify leech contribution to partial salvage

Clinical Implications

Øregaard 2015 documents leech therapy's role in facial dog-bite avulsion salvage. For US clinicians under K040187, the case demonstrates the device's utility in facial trauma beyond ear replantation - specifically, when arterial-only anastomosis is necessary because no suitable veins are available for primary anastomosis. The eventual need for FTSG revision shows leech therapy is not a panacea.

Related Trials

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.